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Month: July 2019

The government has been accused of publishing a d

first_imgThe government has been accused of publishing a “deeply unsatisfying” response to a devastating report by a UN committee that concluded last year that the UK had been “going backwards” on independent living.One disabled people’s organisation (DPO) said the government had been “clutching at straws” in the response in an attempt to persuade the committee that it was implementing the UN Convention on the Rights of Persons with Disabilities (UNCRPD).Another DPO said the response to the UN added to concerns that the government failed to understand the convention and the concept of both independent living and the social model of disability.Last September, an international committee of disabled human rights experts delivered a damning verdict on the UK government’s progress in implementing the convention.The UN committee on the rights of persons with disabilities said it was “deeply concerned” that the government still believed it was a “champion of human rights”, while its chair said that the UK’s cuts to social security and other support for disabled people had caused “a human catastrophe”.A year on, the government has now delivered its response – as requested by the committee – to 25 of the 80-plus recommendations that were made in that report and an earlier inquiry from 2016 which found it guilty of “grave and systematic violations” of the convention.But the government appears to have decided that there was a need for improvements in just six of the 25 areas it was asked to respond to.Its response to most of the recommendations has been to ignore or dismiss the UN’s criticisms and defend its existing policies.Among the recommendations it has ignored are: the need to introduce a legal right to independent living; a call for action to address the disability pay gap; the need for an assessment of the cumulative impact of all its social security cuts and reforms on disabled people; and a call to review the employment and support allowance conditionality and sanction regime.It also ignored the call to develop a “comprehensive plan” – in “close collaboration” with DPOs – aimed at the “deinstitutionalization” of disabled people.But the government does appear to have made a small number of concessions to the committee’s reports.It points in its response to refreshed guidance on employing disabled people (published last month); says the minister for disabled people has convened a cross-sector taskforce on communicating in an accessible way with disabled people; and says the Office for Disability Issues will be “reinvigorating” its “stakeholder engagement” to ensure it engages with more “Disabled People’s User Led Organisations, smaller local stakeholders and individuals”.It also says the government will be refreshing its much-criticised hate crime action plan later this year, including areas focused on disability hate crime, although it makes no reference to the call by the UN committee to combat “negative and discriminatory stereotypes or prejudice” against disabled people that is linked to benefit claimants.And the government report points out that the minister for defence people and veterans announced a review last December of the long-standing “reservation” to the employment rights contained in the convention, which gives the UK an opt-out in relation to jobs in the armed services.DPOs and grassroots groups have been highly critical of the government’s response.Ellen Clifford, campaigns and policy manager for Inclusion London, said: “The first government follow-up report is deeply unsatisfying, in that it demonstrates a failure to substantively engage with the UN disability committee’s recommendations.“Similar to their report as part of the public examination process in 2017, it is little more than a list of legislative and policy measures and spend with no evidence of impact or effectiveness.“The report and cover letter moreover add to concerns around a failure to properly understand either the convention itself, with repeated misinterpretations of the concept of independent living or a social model approach to disability.”She said it was also “quite frankly offensive” for the government to include discussion of autism in the report’s section on health.Clifford added: “There is also a notable lack of mention of engagement with DPOs, which is required under the convention but which the UK government has steadfastly avoided over the last 12 months.“The new general comment from the committee sets out the specific requirement to involve organisations of disabled people in implementation and monitoring of the UNCRPD, yet time and again consultation and engagement with non-user-led charities is being prioritised [by the UK government].”Disability Rights UK (DR UK) accused the government’s report of “clutching at straws” in its attempts to persuade the committee that the convention was being implemented in the UK.Kamran Mallick, DR UK’s chief executive, said: “Although the report says there are plans for engaging with disabled people and our organisations these are yet to take place even though we were told the same thing last year in Geneva. “The creation of the inter-ministerial group on disability and society is welcome and I hope it will really get to grips with implementing our rights, rather than what seems to be the current approach of side-lining the UNCRPD.“Examples of the ‘clutching at straws’ approach include the Care Act principle of wellbeing being used to try and demonstrate a commitment to independent living whereas in reality the two things are not the same. “In fact, the idea of independent living was rejected by the government when the [care bill] was going through parliament.”And he said another of many examples of straw-clutching was that the report claimed the government was following the UNCRPD principle of supported decision-making through the Mental Capacity Act 2005, when in fact the bill it has introduced to amend the act would “take supported decision-making away”.Michelle Maher, of the WOWcampaign, was also heavily critical of the response and said she was “devastated” to see the UK government again ignoring the UN’s recommendations.She said: “The Tory party have dismissed the UN’s findings with their usual disregard of disabled people’s lives in the UK, and the affect of cuts upon us.”She said the government was ignoring the “heart-breaking reality” of the “despair, humiliation and desperation” shown by disabled people as a result of its cuts, while it was “ignoring the truth about the impact”.She said this was why the campaign launched its WOWvoices website, to provide “a space to allow people to have their voices heard, to put the truth out there”.WOW is now pushing for a second House of Commons debate on the need for an assessment of the cumulative impact of the government’s cuts and reforms, something the UN committee called for in its concluding observations and in the November 2016 “grave and systematic violations” report.The government’s response insists yet again that such an assessment “cannot be reliably modelled”, even though the Equality and Human Rights Commission (EHRC), the government’s own social security advisers, and Virginia Bras-Gomes, chair of the UN committee on economic, social and cultural rights – among others – have all insisted that it could and should be done.The government was humiliated in 2014 when the Institute for Fiscal Studies – which ministers repeatedly claimed shared its view that such an assessment would not be possible – published research that included a CIA.EHRC has also published its own CIA report, in March, which calculated its own impact assessment of all the tax, national insurance, social security and minimum wage reforms introduced between May 2010 and January 2018.Maher said the government had “blocked a full assessment at every turn, ignoring any duty of care”, and was “heartlessly cutting, knowing the impact”.She said: “They laid the ground work for cuts by poisonous rhetoric against us and they are continuing.”She called on disabled people and their allies to write to their MP to support WOW’s call for a new House of Commons debate on the need for a CIA.A DWP spokeswoman declined to say if the government agreed that its response accepted the need to make improvements in six of the 25 areas highlighted by the committee, or which of the measures detailed in its response were introduced as a result of the UN committee’s concerns.But she said in a statement: “We have noted all the concluding observations, and not just those that the UN asked us to provide information on this year.“We will respond fully to the UN committee on the rights of persons with disabilities in 2023. This is the deadline set by the committee for the next UK periodic report.“We’re committed to building a society which is fully inclusive of disabled people across every area of their lives, from transport and housing to healthcare and employment.“Our response to the UN sets out our progress over the last year, including the creation of a new inter-ministerial group on disability and society, which will drive progress against the implementation of the UN convention.“While we’ve made significant progress there is always more we can do. We’re determined to continue making progress in creating a society that works for everyone, where all can participate fully.”Picture: Theresia Degener, chair of the committee, speaking last year about the UK’s progress in implementing the conventionlast_img read more


Scarlet Sage Celebrates 20 Years Changes Hands

first_imgLisa Kellman and Dino Lucas are tired, but it’s the kind of fatigue that comes after a day’s work well done. Or in their case, after 20 years’ work well done. The couple, joint owners of the Scarlet Sage apothecary, have retired after pouring some 50 to 60 hours a week into what started as a tiny shop on 22nd and Guerrero streets in 1995. Scarlet Sage, however, will remain open under the new ownership of Laura Ash, a former employee and an accomplished herbalist who has traveled the world studying and teaching traditional methods. She’s dedicated to the alternative medicine as well as the queer community (she moved to San Francisco with her two children) and plans to keep the store almost exactly the same. “We feel really lucky that she wants to do this, and that she is able to do this,” Kellman said. Kellman and Lucas were in their early forties when they opened the shop. It was a wildcrafting trip (on which herbalists sustainably harvest healing plants from the wild and create remedies from them) that sparked their collaboration. Kellman’s background was in accounting, but with time both owners became practiced herbalists, offering mostly Western herbal remedies from actual plant parts to tinctures to essential oils. “It seemed like a great opportunity to use my herbal knowledge in a helpful way,” Lucas said.With time, the two began arranging for classes to be held in the shop, cramming up to 15 people into the 200 square foot space to help customers and other community members understand herbal remedies and take charge of their own health. But the shop and the classes also offered an alternative to mainstream medical practice. “The other thing that’s been important has been to educate people and empower them to take care of their own health, without this hierarchical system that we perceive doctors to be a part of,” Kellman explained.With time, and with a move to a more visible storefront on Valencia, the shop’s clientele grew beyond the local herbalist community to include neighbors looking for a remedy for a particular ailment and immigrants who brought their traditional remedies with them and came in with lists of herbs they needed. To better serve their diverse community, Kellman and Lucas expanded their stock to include some Ayurvedic and traditional Chinese remedies. But it wasn’t just new herbs they brought in.“When we started we were coming out of a medical herbalism focus,” Kellman said. “As we grew, we saw what the needs of the community were…[including] spiritual and metaphysical components.” That included expanded literature, healing crystals, and tarot decks. But herbal remedies continued to be popular. Pregnant women, for example, purchase pounds and pounds of a pregnancy tea containing raspberry and nettle leaves that Kellman and Lucas mix themselves. The stuff flies off the shelves, partly on the recommendation of a local prenatal yoga instructor at Yoga Tree nearby, leading to lines of pregnant women carrying yoga mats forming at the store.The herbal apothecary’s expanded repertoire included remedies for pets. One curious customer tried out a mixture called “life force zest” on none other than his chickens, which suddenly began producing twice as many eggs with stronger shells than before. Skeptical, he withdrew the herbs gain, and found the hens’ output immediately reduced. “It’s a good sign when things work on animals,” Lucas said. “You know it’s not a placebo.” As the shop grew and developed, Valencia street changed around it. Toward 24th street, Lucas said, the street was less popular. “People didn’t want to come down here. They considered it a dangerous area,” she remembered. Conversely, that stretch of Valencia was also home to many businesses, several of them health-related businesses like a chiropractor’s office and a healing center, owned by lesbians. Beretta, Lucas said, was a women-owned cafe with mostly female patrons. A little farther down the street, of course, there were Amelia’s and the Lexington Club. “There was a big history of Valencia being the women’s commerce area,” Lucas said. “And a lot of businesses that were there went out.” The transition to new ownership came shortly after the store moved a few doors down Valencia street, which has, of course, become immensely popular. And though the population has changed, the shop still attracts a diverse clientele, attracted to the shop’s atmosphere.“Despite being retail, it’s a center for different earth based and plant based healing communities,” said Bonnie Rose Weaver, a recent employee of the Scarlet Sage who has since moved on to start her own herb growing venture. “We find a rootedness connecting someone to a perfect flower essence.” Tags: Business • health care • valencia street Share this: FacebookTwitterRedditemail,0%center_img 0%last_img read more


SF Mission Residents Deface Offensive Vice Billboard Ads

first_imgSee update below.A group of residents in a southeasterly swath of the Mission District took cans of spray paint to a cluster of Vice Media billboards Thursday to deface advertisements they found offensive. Among the offending ads is an image of a man castrating a lamb with his teeth, an image of a child with the caption “Right now on TV, 8-year-olds are getting stoned,” and a photo of four shirtless men captioned “Right now on TV, Thomas is getting in touch with bears.”Cynthia Lasden, a teacher who lives near one of the billboards with her nine-year-old daughter, said the ads struck her as crossing a line and inappropriate for children. 0% Share this: FacebookTwitterRedditemail,0%center_img The reference to eight-year-olds getting high, she said, normalizes underage drug use. The naked men and the use of the word “bear” to her connote a level of sexualization that she’d rather not encounter on the street. And the lamb being castrated… “What’s not offensive about that one?” she said.The ads promote a new TV channel from Vice called Viceland. The channel is geared towards younger audiences and will host shows like “Action Bronson & Friends Watch Ancient Aliens” and a nightly newscast.Viceland’s press representative did not return a request for comment by press time.Photo by Lola M. ChavezLasden said she talks to her daughter about difficult subjects, and as a teacher, she’s happy to educate. But she wants to have control over when and how the topics come up.“She knows about marijuana, it’s not a surprise,” she said. “I don’t have any problem talking about these issues with my kid but I want to choose when.”In response, she called together a group of like-minded neighbors to protest the ads by defacing them. She and a few others used spray cans to obscure the objectionable parts of the ads — they replaced the word “stoned” with “library cards” so the text would read “eight year olds are getting library cards” and completely obliterated the lamb genitalia and bare chests of men.“Eight-year-olds are getting stoned? That’s an abuse situation, that’s not advertising,” said Nancy Ivison. “It crosses too many lines all at once in a neighborhood full of children.”In one case they obscured the word “touch,” crossed out the word “bears” and wrote “chipmunks” instead. In another case the word “bears” was replaced with “neighborhood activists.” Below the ad someone added “#stopewwgross” with an arrow pointing to “Viceland.”“Make them into real bears,” one ad-vandal said. The men now sport ears.Photo by Lola M. ChavezBetween targets, Debbie Gish suggested they tone down the satire.“Instead of, ‘Oh, we’re gonna ridicule you back,’ maybe we should just have statements of fact,” she suggested. “Children live here.”Lasden and another ad defacer, 15-year-old Julian Kleppe, said the disgust at the content of the ad had nothing to do with a distaste for the sexual orientation of the subjects, but rather what they found to be the exploitative nature of the imagery.“I feel like they’re objectifying the bear community to generate attention,” Kleppe said.Even among those who agreed the ads were offensive, there were differences of mind.Lloyd T. Ellcessor said he simply stumbled upon the action and joined in because he, too disapproved of the ads — both as a father of young children, six and eight years old, and as someone who had his own first experience with marijuana at eight years old. Adrift at the moment and staying on a friend’s couch, Ellcessor is now also devoutly religious.“The feeling of being next to God is better than any drug any man could ever make,” he said.He added “WWJD” to one of the ads. Later, while others in the group simply deleted the “castrating” in the phrase “Thomas is castrating a lamb,” Ellcessor tried to add “of satan,” turning the phrase into “Thomas is a lamb of satan.” The other neighbors quickly intervened, saying they didn’t want to be associated with that kind of message — but once they left, Ellcessor added it back in, and “of satan” remains scrawled in yellow paint on one of the billboards.Photo by Lola M. ChavezLocal businesses where the billboards are located are staying out of it, though some have been contacted by the frustrated residents. Workers there declined to comment, saying only that they do not have direct dealings with advertisers and their businesses are separate from the billboard business.Two passerby stopped to inquire what was going on as the group went from ad to ad. One said while he understood why the residents took offense, he didn’t see the graffiti-censorship as particularly effective. Another was thrilled, and said the ads had bothered him too.Photo by Lola M. ChavezUpdate: Cynthia Lasden, the teacher who said the ads were inappropriate, said all four billboard locations were being plastered over with new ads. She said a worker changing the posters said his boss had decided to switch out the ads after the controversy.A worker plastering over the graffitied Viceland ads. Photo by Cynthia Lasden. last_img read more


Distillations Taking stock of Bear vs Bull the Cadillac of transit bars

first_imgNever once, not for a moment, in the Bear vs. Bull bar, do you forget that you’re also in a historic movie palace. A statue of a bear fighting a bull (both in boxing gloves) stands at the entrance, with high ceilings, low red lighting, and faux baroque decorations covering every wall on the inside. It falls under the “kitschy but cool” category, or at least “kitschy but so dark that you can’t tell how gaudy it is.” Which was good. I didn’t want this bar to be embarrassing, because I was not only meeting my friends Stuart and Nicole there, I was introducing them for the first time, so, there were some stakes for me on this trip. Bear vs. Bull is the house bar of the Alamo Draft House, which operates in the “New Mission Theater” building at 2550 Mission St. It was first built in 1906, then re-modeled in 1916, and finally closed in 1991. Now it is that rarity, a historic building that has been “re-purposed” to its original purpose, and perhaps this is why the bullshitty décor feels oddly authentic. Sure, it’s stupid, but it kinda belongs, you know? Subscribe to Mission Local’s daily newsletter But while the décor is the first thing anyone trying to drink at Bear vs. Bull will focus on, the most important element of their experience is not the building’s furnishings, but its purpose. It is a bar in a movie theater. It is, along with bars in theaters, bars at airports, and bars at train stations, a perfect example of what I call “transit bars.” Bars that exist not for people to sit and linger at, but to make a pit-stop at while they’re in between points A and B. Bear vs. Bull will fill up with people, right before a movie starts and right after one ends, who will get a quick drink, say “hello” or “goodbye” to their friends, and then move on. There is nothing remotely like the community of regulars and strangers that most bars aspire to, because you don’t go to a bar and then think “screw it, I’ll see a movie,” but rather go to a movie theater and then think “screw it, I’ll have a drink.”That’s the normal course of events, at least, but there is one exception to it, brought about by the one architectural feature of a contemporary movie palace that I haven’t mentioned yet: Bear vs. Bull has air conditioning. And sometimes that makes it a destination bar in a way it never otherwise is.The secret ingredient…That’s why I was there on a Wednesday afternoon. I had no intention of seeing a movie. And I wasn’t the only one: The bartender told me that over the superheated weekend, the place had not only been packed all Saturday, but they’d broken their record for piña coladas sold by a mile.I mean, there are only so many bars with air conditioning in this city, after all.Bear vs. Bull has a menu, but it’s almost entirely a cocktail menu. Most of the beer list is written on a chalkboard off in one corner of the bar … which is a great idea, except that it’s a back corner that isn’t actually easy to see or read from most vantage points, and even the best idea turns out pretty terrible if it’s badly executed. If I’d actually wanted a beer, I’d be pissed. Nicole, who has the beer taste of an illiterate peasant whose taste buds died in the plague, would later order a beer and find the process only moderately annoying. I, however, was enough of a beer snob that the beer menu interested me a lot less than the cocktails. If nothing else, you have to give Bear vs. Bull points for novelty: the menu starts off with a list of boilermakers, concoctions that I almost never see highlighted in this city anymore. Well, not “highlighted” – a lot of places offer beers and shots. But Bear vs. Bull is at least trying to play with the formula, pairing ciders with shots of rum and beers with apple brandy as well as the more traditional PBR and Jameson. This is excellent. There’s a whole forgotten frontier here. But I was first struck by the offering of an old fashioned made with a private barrel of Old Scout bourbon. There are a small number of bars in this town that work directly with distillers to develop their own private and exclusive barrels, and even though it’s honestly as much stunt as it is craft, it speaks to my jaded little heart. So that’s where I started, and God damn it was a good old fashioned. Would order again. Stuart arrived first, and ordered the La Paloma (Pueblo Viejo Blanco Tequila, Lime, Agave, Grapefruit Bitters, Mexican Squirt), which he strongly approved of, and we started talking about old business. It’s been a while since we’ve seen each other, and I’m kind of mad at Stuart, and more mad at some of the people we have in common, but dammit, I like the guy and don’t want this to be a problem. But sometimes, when you’re drinking together, you don’t really get to decide what is and isn’t going to turn into a problem, you know? And before we were even on to our second drink I was challenging him to a public debate while saying things like “I will not be erased.” If you’re going to say things like that, I highly recommend saying them in a historic building. It adds extra gravitas to the whole affair. Demanding an acknowledgment of shared history in a refurbished hipster pop-up is toxically ironic.My second drink was a Cool Jerk (Plantation Pineapple Rum, Eldorado 3yr Rum, Ancho Reyes, Falernum, lime, pineapple, mint, spicy salted rim), which I strongly approved of, while Stuart moved to white wine, and for a little while the two of us were back on an even keel, laughing about our shared history instead of fighting over it. Every friendship fights differently. My third drink was the Shanghai Bastard (El Dorado 12yr Rum, Encanto Pisco, Honey, Ginger, Lime, Angostura), and at this point I should emphasize that just because I was ordering rum and tiki-esque drinks doesn’t mean that’s what the bar itself leans towards – it was just the mood I was in. Maybe rum paired well for me with the air conditioning. That could be a thing. Or maybe it’s that I got back from rum tastings in Puerto Rico not too long ago, and still have the flavors on my mind. Perhaps they will not be erased.center_img “Shanghai bastard?” Stuart asked me. “Is that supposed to be a comment on the company you’re keeping?”“Oh, God no,” I told him. “You’re not a Shanghai bastard. But, man, the first drink I ordered after you arrived was a ‘cool jerk.’ Pay attention.”The drinks are good – across the board – but I find myself a little depressed by the prices. It wasn’t so long ago in this city that a $16 cocktail was supposed to be something special, instead of quite good. The mixology at Bear vs. Bull is better than it ought to be for a transit bar, but not quite as good as it should be for the price. On the other hand, movie popcorn costs too fucking much too, and I’ll still buy a bag if I’m in the mood.Nicole arrived a moment later, and since I want them to like each other, I was on my best behavior. The truth is that Stuart and I aren’t good at fighting: We tend to stab each other deep when we mean to punch in the arm. Air conditioning and a third party both helped a lot. The drinking didn’t help so much, but dammit, that’s what we do. Surrounded, in this case, by tourists who came to San Francisco and for some reason wanted to see a movie in the late afternoon. I usually hate transit bars. But if you bring friends, I think this is the best of the breed.  Email Addresslast_img read more


ALL the stats as Saints host London Broncos tonigh

first_imgALL the stats as Saints host London Broncos tonight!Last Ten Meetings:St Helens 38, London Broncos 10 (SLR24, 9/8/13)London Broncos 21, St Helens 14 (SLR13, 27/4/13)St Helens 30, London Broncos 0 (SLR26, 31/8/12)London Broncos 24, St Helens 34 (SLR1, 4/2/12)Harlequins 16, St Helens 34 (SLR27, 10/9/11)St Helens 16, Harlequins 27 (SLR5, 11/3/11)St Helens 32, Harlequins 18 (SLR22, 18/7/10)Harlequins 10, St Helens 30 (CCR5, 9/5/10)Harlequins 24, St Helens 32 (SLR11, 10/4/10)Harlequins 24, St Helens 44 (SLR22, 25/7/09)Super League Summary:St Helens won 36 (includes win in 2003 play-offs)London Broncos won 62 drawsHighs and Lows:St Helens highest score: 62-16 (H, 2003) (Widest margin: 54-0, A, 2008)London Broncos highest score: 40-6 (H, 2002) (also widest margin)First Utility Super League Leading Scorers:Tries:1 Tom Makinson (St Helens) 122 Ryan Hall (Leeds Rhinos) 103 = Justin Carney (Castleford Tigers) & Elliott Whitehead (Catalan Dragons) 95 = Michael Shenton (Castleford Tigers) & Omari Caro (Hull Kingston Rovers) 8Goals:1 Danny Brough (Huddersfield Giants) 392 Kevin Sinfield (Leeds Rhinos) 363 Marc Sneyd (Castleford Tigers) 354 Luke Walsh (St Helens) 325 = Jarrod Sammut (Wakefield Trinity Wildcats) & Danny Tickle (Widnes Vikings) 30Goals Percentage:1 Chris Bridge (Warrington Wolves) 90.00 (9/10)2 Jamie Foster (Bradford Bulls) 86.36 (19/22)3 = Marc Sneyd (Castleford Tigers) 83.33 (35/42) & Jarrod Sammut (Wakefield Trinity Wildcats) 83.33 (30/36)5 Danny Tickle (Widnes Vikings) 81.08 (30/37)Points:1 Kevin Sinfield (Leeds Rhinos) 882 Danny Brough (Huddersfield Giants) 863 Jarrod Sammut (Wakefield Trinity Wildcats) 804 Marc Sneyd (Castleford Tigers) 765 Luke Walsh (St Helens) 72last_img read more


HALF Season Tickets for the rest of the 2015 First

first_imgHALF Season Tickets for the rest of the 2015 First Utility Super League campaign are now on sale!Not only are they great value for money and save ££ against matchday prices, but with Saints well placed in the top four if they remain there after 23 regular rounds, your package will include an extra home game for no additional cost.Plus, it secures your place for the big derby against the Wigan Warriors on June 12.And, as well as getting full season ticket status for the remainder of the 2015 season, you are entitled you to the renewal price on a full season ticket for 2016!Being a Season Ticket holder entitles you to the following benefits:Access to the First Utility Super League regular season home games against Salford Red Devils (June 5), Wigan Warriors (June 12), Huddersfield Giants (July 10), Hull KR (july 24) – plus either three or four additional Super 8 home games, depending on Saints’ final league position. 10% Off Official Saints merchandise (T&Cs apply)Priority tickets for major games Discounted away travel Free Tickets For all Junior Season Ticket Holders to all remaining 2015 Saints Away league games (Subject to availability)VIP Hospitality upgrade In the Hatton’s Travel Sponsors Lounge, including three-course meal for a discounted season ticket only pricePlease note terms and conditions apply to all benefits above, these can be viewed here – the ticket does not include any First Utility Super League Semi-finals played at Langtree Park.To buy and view prices click here (and click on the season ticket tab).For further information contact the Ticket Office on 01744 455 052.#oursaintslast_img read more


WORLD Club Series tickets are now on General Sale

first_imgWORLD Club Series tickets are now on General Sale.Saints will face Sydney Roosters at Langtree Park on Friday February 19 (8pm) as part of the prestigious World Club Series.It is a rematch of the first ever World Club Challenge game which saw the then Eastern Suburbs face St Helens in 1976.The 2016 Roosters will come to the town having won the Minor Premiership for the last three seasons – and are packed with a host of NRL stars such as Shaun Kenny-Dowell, Jared Waerea-Hargreaves and Mitchell Pearce.Saints will no doubt be blooding new signings Lama Tasi, Dominique Peyroux, Theo Fages and Jack Owens too.It will be a real Super League v NRL test!They are priced at:Hattons Solicitors West Terrace, East Terrace and Family Stands:Adult – £22.50OAP and Young Adult – £15.50Junior – £10Solarking South and Totally Wicked North Stands:Gold:Adult – £30OAP and Young Adult – £22.50Junior – £12Silver:Adult – £28OAP and Young Adult – £20.50Junior – £12Bronze: Adult – £25OAP and Young Adult – £18.50Junior – £10Tickets can be bought by popping into the Ticket Office at Langtree Park, by calling 01744 455 052 or online here.A package for all three games (Leeds v North Queensland, Wigan v Brisbane) costs £60 and can be purchased by visiting www.rugbyleaguetickets.co.uk or calling the Rugby League Ticket Hotline on 0844 856 1113.last_img read more


Tickets go on open sale today for the 2019 Wembley

first_imgTickets go on open sale today for the 2019 Wembley Stadium showpiece, along with dates for the eight rounds on the Road to Wembley – which will begin next month with the draw for the First Round to be played on January 26-27.But for supporters of Championship and League One clubs, there’s an extra reason to make a note of Challenge Cup Final Day – as they will have a second chance to reach Wembley next year, in the 1895 Cup.Full details will be announced with the Betfred Championship and League One fixtures on Sunday week, but the clubs have agreed after a meeting last week to introduce the new competition.All but one of the 12 English Championship clubs have previously won the Challenge Cup, sharing a total of 30 Cup wins – from Batley, who were the first winners in 1897, to Bradford Bulls, the most recent to do so in 2003.In addition three League One clubs – Hunslet, Oldham and Workington Town – are also former Challenge Cup winners, although in Oldham’s case famously never at Wembley.But only Sheffield Eagles and Bradford have played in a Challenge Cup Final at Wembley during the Super League era (since 1996), and none of the Championship or League One clubs have reached the new Wembley Stadium since the Challenge Cup Final returned to its spiritual home in 2007.The introduction of the 1895 Cup means that there will be three Finals at Wembley Stadium next August – as the Steven Mullaney Memorial Match (the RFL Champion Schools Final for Year 7s), which has long been established as a popular curtain-raiser to the Challenge Cup Final, will also remain a key part of the day.The RFL have also extended their partnership with Wembley – which has staged 76 Challenge Cup Finals since the first between Wigan and Dewsbury in 1929 – until 2027, which will therefore be the 85th at the Stadium.Next year’s Challenge Cup Final Day will stick to what has become a regular place on the calendar, the August Bank Holiday Weekend. But in 2020, there will be a move forward to Saturday July 18.Ralph Rimmer, the chief executive of the Rugby Football League, said: “This is a significant and exciting day for the Challenge Cup, and the game’s relationship with Wembley Stadium.“Next year we will celebrate the 90th anniversary of the first Challenge Cup Final at Wembley in 1929. Rugby League is proud of the length and strength of that association – Wembley Stadium has been the setting for so many of the greatest matches and memories in the game’s history, with Catalans Dragons writing another chapter when they became the first overseas club to win the Cup earlier this year.“We are therefore delighted to confirm the extension of that relationship until 2027.“We believe the introduction of the 1895 Cup will give that relationship another boost. It’s a recognition that the game has changed since the onset of full-time professionalism in the Super League era, meaning that for a good number of the Championship and League One clubs who have won the Challenge Cup in the past, reaching Wembley currently seems a distant dream. This innovation makes that dream of Wembley much more realistic and achievable.“We’ve seen in football, with the EFL Trophy that was introduced for teams for the third and fourth tiers of their professional structure as the Associate Members’ Cup in 1983, that the introduction of a realistic additional chance to reach Wembley can have a rejuvenating effect on clubs.“With the 1895 Cup, we want to recognise the contribution of our non-Super League clubs to the game’s history since its founding as the Northern Union 123 years ago – and provide an exciting new chance for their players and supporters to taste the magic of Wembley.“With the Steven Mullaney Memorial Match continuing to provide a unique opportunity for some potential future stars to play at Wembley Stadium, we’ve tried to create a Challenge Cup Final Day package which will breathe new life into Rugby League’s big day out.”Confirmed Challenge Cup Round Dates:Round 1 – 26th/27th January Round 2 – 9th/10th February Round 3 – 9th/10th March Round 4 – 30th/31st March Round 5 – 13th/14th April Round 6 – 11th/12th May Quarter-Finals – 1st/2nd June Semi-Finals – 27th/28th July Final – Saturday 24th August – Wembley Stadium connected by EEThe draw for Round 1 of the 2019 Challenge Cup will take place week commencing December 10. Further details to follow soon.last_img read more


The game gets underway at 7pm and entry is £3 for

first_imgThe game gets underway at 7pm and entry is £3 for Adults and £1 for Concessions and Juniors.LFC season ticket holders and members can watch the game for free.Tickets can be purchased in advance from the Ticket Office and on the day of the game from the turnstiles and all fans will be seated in the Totally Wicked North Stand.You can also buy online here for collection up until 5pm.last_img


10th annual TouchaTruck event rolling into Wilmington

first_img The 10th annual Touch-A-Truck event is being held Sunday April 28th from 11 a.m. until 3:30 p.m. at The Pointe at Barclay. Tickets for the event are $6 a person or $20 for a four pack.For more information you can visit their website. WILMINGTON, NC (WWAY)– The Junior League of Wilmington President Sasha Kammer and Vice President of Fund Development Janison Dillon sat down with WWAY’s Amanda Fitzpatrick to talk about their 10th annual Touch-A-Truck event.Touch-A-Truck is meant to be be an educational community event. Children can see and touch heavy machinery and meet the people who build, protect and serve the Wilmington community.- Advertisement – last_img


Wounded man in Marsalforn detained for aggressive behaviour

first_imgA man who was found wounded in Marsalforn, was detained after he reacted aggressively towards the police as well as in hospital. The police intervened after it received reports of aggressive person. Police received a phone call at around 11:30pm, informing them about an aggressive person who is damaging things in Triq il-Port. Upon arriving at the scene, they were met with a man sitting on the ground and covered in blood. An ambulance was called on site. However while waiting, the person became aggressive towards the police. Upon the arrival of the ambulance, the person also acted in an aggressive manner towards the paramedics, and this behavior continued at the Gozo General Hospital.The man who hails from Eritrea is 28 years old.He was kept under arrest pending further investigations. WhatsApp <a href=’http://revive.newsbook.com.mt/www/delivery/ck.php?n=ab2c8853&amp;cb={random}’ target=’_blank’><img src=’https://revive.newsbook.com.mt/www/delivery/avw.php?zoneid=97&amp;cb={random}&amp;n=ab2c8853&amp;ct0={clickurl_enc}’ border=’0′ alt=” /></a> SharePrintlast_img read more


Intel to train 5 million African females in ICT

first_imgAdvertisement Chipsets-maker, Intel, has confirmed its commitment to closing the gender gap in technology participation in Africa through its digital literacy programme for young women in developing countries, ‘She Will Connect’.Launched in 2013, the project wants to reduce gender gap by 50% and is planning to reach five million women and girls across Africa by 2020.At a recent capacity building workshop on ICT organised by Intel, for women tech journalist in Lagos, Intel announced it will release its online learning platform and as well partner with Internet.org in Nigeria by August. – Advertisement – Mr. Olubunmi Ekundare the Managing Director Intel West Africa said that the company will provide technical resources and expertise to deliver digital literacy training, online peer networks and gender relevant content to empower young girls and women in Nigeria.‘She will Connect’ partners include World Pulse, RockeFeller foundation, Women’s technology empowerment centre (W-Tec), Youth for Technology Foundation (YTF), Junior Achievement Nigeria (JAN), Women in Technology (WITIN).Via Tech Cablelast_img read more


STAR PREVIEW Bayern Munich v Barcelona

first_img[dropcap]B[/dropcap]arcelona have won 17 of their last 18 matches including a stunning 3-0 first leg success which should be more than enough to have booked their place in the 2015 Champions League Final.Neymar, Luis Suarez and Lionel Messi are a formidable strike force and to compound problems for Bayern they are without wingers Franck Ribery and Arjen Robben tonight whilst Barcelona are at full strength – a luxury at this stage of a long season.Not only that, Barca rested five players including Andres Iniesta, Jordi Alba and Sergio Busquets but still beat Real Sociedad 2-0 to boost their domestic title hopes.Bayern boss (and former Barcelona manager) Pep Guardiola said: “The only way we can make the final is by playing better than Barcelona and doing what we did in the second half [of the first leg]. Our only desire is try until the end. We are the Bundesliga champions and we’ve had an extraordinary year, despite some difficulties.”Barcelona certainly won’t be taking this as a completely formality. After all, the German champions lost the first leg of their quarter-final 3-1 against Porto but came back to win the home leg 6-1.Bayern Munich v BarcelonaUEFA Champions League Semi-Final 2nd Leg7.45pm ITVHEAD TO HEAD RECORD(Maximum 10 matches)May 2015 Champions League Barcelona 3-0 B MunichMay 2013 Champions League Barcelona 0-3 B MunichApr 2013 Champions League B Munich 4-0 BarcelonaApr 2009 Champions League B Munich 1-1 BarcelonaApr 2009 Champions League Barcelona 4-0 B MunichNov 1998 Champions League Barcelona 1-2 B MunichOct 1998 Champions League B Munich 1-0 BarcelonaApr 1996 UEFA Cup Barcelona 1-2 B MunichApr 1996 UEFA Cup B Munich 2-2 BarcelonaThere’s little to choose between the two sides on Star Sports. I’ll have a little interest on the DRAW at 11/4 – a result that will do little for Bayern Munich bar restore some lost pride.RECOMMENDED BETS (scale of 1-50 points)BACK DRAW for 6 points at around 11/4 with Star SportsRETURN SINCE START OF WORLD CUP: PROFIT 56.19 POINTSWhat’s your view? CALL STAR SPORTS 08000 521 321last_img read more


STAR PREVIEW Arsenal v Man City

first_img[dropcap]I[/dropcap]’ve always said the fixture list generator has a great skill in producing ‘random’ fixtures.We are truly blessed to have the computer select Arsenal v Man City as the final Premier League fixture before Christmas !!! Conspiracy theories aside for one moment, because even the fixture list computer couldn’t have predicted the scenario that both sides need a win tonight in order to keep tabs on …….. Leicester.That’s exactly where we are at. A point for either side would still leave Leicester with a four point cushion at the top – and as the stats book tells us ‘five of last the last six seasons has seen the team who have led on Christmas Day go on and be crowned champions’.The hosts name an unchanged side from last weekend’s 2-0 away win at Aston Villa.Manuel Pellegrini has given a start to Aguero who returns from injury with Raheem Sterling on the bench.Pellegrini said: “We must consider Leicester – they are still top of the table. United are just a few points behind us. Tottenham can be involved, so can Liverpool and Crystal Palace. It’s impossible just to think there are two teams involved in the title.”SO – it’s a six horse race then ??? The outright odds say not with it still looking a match between Man City and Arsenal and around 10/1 bar.Arsenal v Man CityPremier League20:00 Sky Sports 1 / Sky Sports 1 HDHEAD TO HEAD RECORD(Maximum 10 matches)Jan 2015 PREMIER Man City 0-2 ArsenalSep 2014 PREMIER Arsenal 2-2 Man CityAug 2014 COMMUNITY SHIELD Arsenal 3-0 Man CityMar 2014 PREMIER Arsenal 1-1 Man CityDec 2013 PREMIER Man City 6-3 ArsenalJan 2013 PREMIER Arsenal 0-2 Man CitySep 2012 PREMIER Man City 1-1 ArsenalApr 2012 PREMIER Arsenal 1-0 Man CityDec 2011 PREMIER Man City 1-0 ArsenalNov 2011 CARLING CUP Arsenal 0-1 Man CitySTARTING XIArsenal33 Cech24 Bellerín04 Mertesacker06 Koscielny18 Monreal20 Flamini16 Ramsey14 Walcott11 Özil28 Campbell12 GiroudManchester City01 Hart03 Sagna30 Otamendi20 Mangala11 Kolarov25 Fernandinho42 Y Touré18 Delph21 Silva10 Agüero17 De BruyneThe draw tonight is 12/5 with Star Sports and the option I like best. Leicester won’t mind that too much either…..RECOMMENDED BETS (scale of 1-50 points)BACK DRAW for 5 points at around 12/5 with Star SportsRETURN SINCE START OF WORLD CUP: PROFIT 87.56 POINTSWhat’s your view? CALL STAR SPORTS 08000 521 321last_img read more


STARTERS ORDERS Friday

first_imgWhat’s your view?CALL STAR SPORTS ON 08000 521 321 [dropcap]W[/dropcap]elcome to Starters Orders. Our daily midday update from the trading room at Star Sports with our key market movers for the day across all sports.Friday 19 FebruaryRACING2.20 LingfieldChelwood Gate 5/2 > 7/42.45 SandownKatie Too 7/4 > 5/43.40 FakenhamSummer Sounds 8/1 > 5/14.10 FakenhamGood Egg 13/2 > 9/24.20 SandownBertie Boru 7/1 > 5/15.05 LingfieldDelagoa Bay 9/2 > 3/15.20 WolverhamptonRampers 11/2 > 3/16.35 DundalkGrey Danube 9/1 > 6/17.05 DundalkModem 8/1 > 9/27.50 WolverhamptonObboorr 5/1 > 3/1CHELTENHAM MOVERALTIOR 6/1 > 4/1Supreme NovicesRealisation that Min will go to Cheltenham with still something to prove.LIVE FOOTBALLFRIDAYScottish Premiership19:45 BT Sport 2 / BT Sport 2 HD / BT Sport Extra 114/5 Partick Thistle 11/10 Aberdeen 9/4 DRAWSATURDAYChampionship12:30 Sky Sports 1 / Sky Sports 1 HD7/4 Cardiff City 13/8 Brighton & Hove Albion 11/5 DRAWFA Cup 5th Round12:45 BT Sport 2 / BT Sport 2 HD / BT Sport Ultra HD1/2 Arsenal 6/1 Hull City 3/1 DRAW(All prices subject to fluctuation)last_img read more


Major Programs at Rice Available on RealAudio Arafat and De Lange –

first_imgAddThis ShareMedia Advisory CONTACT: Philip Montgomery PHONE: (713) 831-4792E-mail: pmontgom@rice.edu 97-93MAJOR PROGRAMS AT RICE AVAILABLE ON REALAUDIOArafat and De Lange – Woodlands Conference Online WednesdayAn online recording of Palestine National Authority President Yasir Arafat’sremarks at Rice University will be available on the World Wide Web at http://realaudio.rice.edu within fiveminutes of the conclusion of his talk on March 5. Arafat will begin speaking atapproximately 7 p.m. The program is scheduled to end around 7:45 p.m.Two luncheon speakers from the De Lange – Woodlands Conference on SustainableDevelopment will also be featured March 5 on RealAudio. Rice UniversityPresident Malcolm Gillis will deliver a lecture titled “The Economics of theDeveloping World: Poverty and Environment,” and Robert Kates with the NationalAcademy of Sciences/National Research Council’s Board of Sustainable Developmentwill talk about “Population and Consumption: From More to Enough.” Both speecheswill be available by 3 p.m.To listen to the speeches online you must use “RealAudio Player,” a freedownloadable software. The site http://realaudio.rice.edu is now active andcontains a link to the Web page from which RealAudio Player can be downloaded.With the RealAudio Player installed on your computer, simply click on the Arafatlink located at http://realaudio.rice.edu. The file willbegin “streaming” or sending the speech to your computer. If you need assistanceor have questions regarding the RealAudio Player, call Philip Montgomery at(713) 831-4792.###last_img read more


Red means go to therapeutic viruses

first_imghttp://news.rice.edu/files/2015/11/1207_VIRUS-2a-web.jpgRice University graduate student Eric Gomez holds a spiral-patterned mask he used to control gene-expression patterns in a petri dish. Cells in the dish contained a modified virus that responded to red light and delivered their genetic cargoes to the nuclei of cells. (Credit: Jeff Fitlow/Rice University) http://news.rice.edu/files/2015/11/1207_VIRUS-3-web.jpgRice University bioengineer Junghae Suh, left, and graduate student Eric Gomez led a study in which proteins that respond to light helped viral capsids deliver their contents to the nuclei of cells. The researchers see their technique as a way to control gene expression. (Credit: Jeff Fitlow/Rice University)Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,910 undergraduates and 2,809 graduate students, Rice’s undergraduate student-to-faculty ratio is 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for best quality of life and for lots of race/class interaction by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance. To read “What they’re saying about Rice,” go http://tinyurl.com/AboutRiceUniversity. ShareEditor’s note: Links to images for download appear at the end of this release.David Ruth713-348-6327david@rice.eduMike Williams713-348-6728mikewilliams@rice.eduRed means ‘go’ to therapeutic virusesRice University scientists use light to switch viral activity and deliver cargoes to cells HOUSTON – (Dec. 1, 2015) – Light is helping Rice University scientists control both the infectivity of viruses and gene delivery to the nuclei of target cells.The researchers have developed a method to use two shades of red to control the level and spatial distribution of gene expression in cells via an engineered virus.Although viruses have evolved to deliver genes into host cells, they still face difficulties getting their payloads from the cytoplasm into a cell’s nucleus, where gene expression occurs. The Rice labs of bioengineers Junghae Suh and Jeffrey Tabor have successfully found a way to overcome this critical hurdle.The team’s research appears this week in the American Chemical Society journal ACS Nano.The result from labs at Rice’s BioScience Research Collaborative combines Suh’s interest in designing viruses to deliver genes to target cells with Tabor’s skills in optogenetics, in which light-responsive proteins can be used to control biological behavior.They built custom adeno-associated virus (AAV) vectors by incorporating proteins that naturally come together when exposed to red light (650-nanometer wavelengths) and break apart when exposed to far red (750-nanometer wavelengths). These naturally light-responsive proteins help the viral capsids – the hard shells that contain genetic payloads –enter the host cell nuclei.AAV has been the vector of choice for gene editing by way of CRISPR/Cas9, a technique that shows promise for curing some genetic diseases, but cell nuclei present a problem, Suh said.“Viruses in general are relatively efficient at delivering genes into cells, but they still experience great limiting barriers,” she said. “If you add these viruses to cells, most of them seem to hang out outside of the nucleus, and only a small fraction make their way inside, which is the goal.”She said the team drew upon the Tabor lab’s expertise in optogenetics to increase the AAVs’ efficiency. “Jeff works with many different types of light-responsive proteins. The particular pair we decided upon was first identified in plants.“Light is really nice because you can apply it externally and you can control many aspects: at what areas the light is exposed, the duration of exposure, the intensity of the light and, of course, its wavelength,” she said.The protein pair comprises phytochrome B and its binding partner phytochrome interacting factor 6 (PIF6), both found in thale cress. The researchers generated host cells that express phytochrome B tagged with a nuclear localization sequence, a small peptide known to help shuttle proteins into the nucleus more effectively. The smaller PIF6 was then attached to the outside surface of the virus capsid.“When the viruses get internalized into a host cell, they accumulate around the nucleus naturally,” Suh said. “Under nonactivated conditions, most of the viruses are stuck there. But when we shine activating red light on the cells, these two plant proteins dimerize — they come together — and because of the nuclear localization tag on the phytochrome B, the virus is dragged into the nucleus.”This is the first time optogenetic proteins have been used to control the infectivity of viruses, she said, adding, “We didn’t think it would work as well as it did.”Lead author Eric Gomez, a graduate student in Suh’s lab, and co-author Karl Gerhardt, a graduate student in Tabor’s lab, demonstrated the technique by activating patterns of AAV-infected cells in petri dishes by shining red light at them through masks.Suh said the platform may be used in the future to control what cells and tissues express a gene and at what level. The strategy could also find use in tissue-engineering applications like bioscaffolds for implantation. “Here, you might want to coax stem cells to develop into the right cells in some kind of spatially coordinated fashion,” she said.Use in the body is further off, because externally applied red light only goes so far through tissue to reach targets. “Ultimately, it’s going to depend on the device you use to deliver the light,” she said. “But we imagine cases where you could use a catheter to go to the spot where you want the viruses to be much more infectious.”Suh said the Rice labs are working to make the next generation of capsids both more effective and more deliverable. “This is just the first step,” she said. “We have a lot of questions, like ‘Can we really do this in vivo?’ kind of questions.“There have been a handful of papers trying to make the virus-infectious process responsive to light, but they were before the era of optogenetics,” Suh said. “They were using other types of synthetic molecules to make viruses light-responsive.“It seems using what Mother Nature has already provided in the form of light-responsive proteins works really well for us.”Rice alumnus Justin Judd, now a postdoctoral researcher at the University of California, San Francisco, is co-author of the paper. Suh is an associate professor of bioengineering. Tabor is an assistant professor of bioengineering.A National Academy of Sciences Ford Foundation Fellowship to Gomez supported the research.-30-Read the abstract at http://pubs.acs.org/doi/abs/10.1021/acsnano.5b05558Follow Rice News and Media Relations via Twitter @RiceUNewsRelated Materials:Synthetic Virology Laboratory (Suh): https://sites.google.com/site/suhsynvirol/Tabor Lab: http://www.taborlab.rice.eduGeorge R. Brown School of Engineering: http://engineering.rice.eduRice Department of Bioengineering: http://bioe.rice.eduImages for download: http://news.rice.edu/files/2015/11/1207_VIRUS-1-web.jpgHitting a petri dish of cells that contained a modified virus with patterned red light encouraged gene expression that matched the pattern. The experiment by scientists at Rice University proved the effectiveness of a new gene delivery system that can be controlled with light. (Credit: Eric Gomez/Rice University) AddThislast_img read more


Protein spy gains new abilities

first_imghttp://news.rice.edu/files/2017/04/0501_PROTEIN-3-WEB-1a6deye.jpgRice University graduate student Emily Thomas led a team that created a method to label proteins being produced in cells. The labels enable researchers to acquire a snapshot of proteins being produced by a cell at a given time. (Credit: Jeff Fitlow/Rice University)Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,879 undergraduates and 2,861 graduate students, Rice’s undergraduate student-to-faculty ratio is 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for happiest students and for lots of race/class interaction by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance. To read “What they’re saying about Rice,” go to http://tinyurl.com/RiceUniversityoverview. ShareEditor’s note: Links to high-resolution images for download appear at the end of this release. David Ruth713-348-6327david@rice.eduMike Williams713-348-6728mikewilliams@rice.eduProtein ‘spy’ gains new abilitiesRice University researchers build a novel switch to facilitate tagging of proteins in a cell HOUSTON – (April 27, 2017) – Rice University scientists have learned to spy on cells with a divide-and-conquer strategy to label proteins.Graduate student Emily Thomas, synthetic biologist Jonathan Silberg and their colleagues built upon established techniques that attach bio-orthogonal (noninterfering), artificial amino acids to transfer RNA (tRNA), which are used by ribosomes to synthesize proteins.Because the amino acids are “noncanonical,” they are effective tags that help researchers identify proteins being synthesized in a cell. The Rice lab’s breakthrough was the discovery of a tRNA synthetase that only adds the amino acid to the tRNA when it binds a chemical. When prompted, the tRNA synthetase charges a tRNA with the bio-orthogonal amino acid, which is then used by ribosomes to insert the tag into proteins made in the cell.The study appears in the American Chemical Society journal ACS Synthetic Biology.Rice scientists have discovered a method to tag proteins with a controllable enzyme switch. When prompted, fragments of a tRNA synthetase come together and charge a tRNA with a bio-orthogonal amino acid (N3), which is inserted as a recognizable tag into all subsequent proteins made in the cell. Courtesy of the Silberg Research GroupThese bio-orthogonal tags give researchers a snapshot of total protein synthesis in the cell. “Instead of physically separating a cell from a mixture to find the proteins being made, we can use this engineered switch to put what amounts to a fishhook on every protein in a specific cell,” Silberg said. “This approach will allow us to increase spatial and temporal control over the tagging of proteins synthesized in a given cell.”Since many proteins appear and disappear during the development of an organism or the spread of a disease, the technique could be helpful to identify cellular changes that underlie disease. Thomas characterized her technique as a “protein spy.”“It spies on what proteins are being made inside the cell,” she said. “Current technologies just spy on everything, but I want to be more specific. I want more control over when I turn my spy on or off, so I can track only the cells I’m interested in.”The researchers used an azidonorleucine (Anl) amino acid to tag proteins in Escherichia coli bacteria cells. Thomas’ engineered switch is controlled like a computer program’s AND gate. The switch only charges tRNA with Anl efficiently when the switch is synthesized and a chemical is present in the cell to flip the switch.Rice University synthetic biologist Jonathan Silberg and graduate student Emily Thomas. Photo by Jeff FitlowSilberg said the technique will provide new control over protein transcription and tagging to researchers. “In human biology, a lot of the control comes at the DNA level, but over the past 20 years it’s become apparent that a lot of control comes at the protein level as well,” he said. “We have fewer genes in our genome than people originally expected because there’s this other layer of complexity in the proteome, the collection of proteins expressed by the genome.“Proteins are the business side of the cell,” he said. “They provide structure and do a lot of the signaling within a cell. They give rise to a lot of the complexity we observe. In the future, our technique could help people understand the details of a disease by providing snapshots of proteins synthesized in specific cells at different times during development and allowing comparisons of healthy and diseased cells.“The prospect of doing this in humans is the genetic technology equivalent of going to Mars right now,” Silberg said. “It’s far out.”Co-authors of the paper are Rice alumnus Naresh Pandey, graduate student Sarah Knudsen and Zachary Ball, an associate professor of chemistry. Silberg is an associate professor of biosciences.The research was supported by the National Science Foundation, the Robert A. Welch Foundation, the John S. Dunn Collaborative Research Award, the National Aeronautics and Space Administration, the Keck Center of the Gulf Coast Consortia, the Houston Area Molecular Biophysics Program and the National Institute of General Medical Sciences.-30-Read the abstract at http://pubs.acs.org/doi/abs/10.1021/acssynbio.7b00100Follow Rice News and Media Relations via Twitter @RiceUNewsRelated materials:The Silberg Research Group: www.bioc.rice.edu/~joff/Wiess School of Natural Sciences: http://natsci.rice.eduImages for download: http://news.rice.edu/files/2017/04/0501_PROTEIN-1-WEB-1gbzzvp.jpgRice University scientists have discovered a method to tag proteins with a controllable enzyme switch. When prompted, fragments of a tRNA synthetase come together and charge a tRNA with a bio-orthogonal amino acid (N3), which is inserted as a recognizable tag into all subsequent proteins made in the cell. (Credit: The Silberg Research Group/Rice University) http://news.rice.edu/files/2017/04/0501_PROTEIN-2-WEB-1dor0do.jpgRice University synthetic biologist Jonathan Silberg and graduate student Emily Thomas in the lab. They led the discovery of a method to rapidly trigger the universal tagging of proteins being produced by a cell. (Credit: Jeff Fitlow/Rice University) AddThislast_img read more


Houston needs better public transit to job centers study concludes

first_img April 2017, Houston, Texas: The metro light rail heading north through the traffic light towards downtown Houston. Photo credit: 123rf.com/Rice University ShareRice UniversityOffice of Public Affairs / News & Media RelationsNEWS RELEASEDavid Ruth713-348-6327david@rice.eduAmy McCaig713-348-6327amym@rice.eduHouston needs better public transit to job centers, study concludesHOUSTON – (Oct. 11, 2018) – Houston’s job centers need to be better connected to the regional transportation network, according to a new report from Rice University’s Kinder Institute for Urban Research. Return to article. Long DescriptionThe metro light rail heading north through the traffic light towards downtown Houston. Photo credit: 123rf.com/Rice University“Accessing Opportunity: Employment and Commuting Patterns Among Low, Medium and High-Wage Workers in Houston” explores how workers get around in an urban setting. Specifically, the report used data from the Longitudinal Employer-Household Dynamics (LEHD) program and the American Community Survey to examine travel patterns between home and work in Harris County.Kinder Institute researchers Jie Wu, Mingming Zhang and Grant Patterson and Kinder Fellow Yujie Hu authored the report. In addition to a countywide analysis, they conducted case studies that showed commuting patterns for different wage groups vary.The three Houston job centers the report focuses on are downtown, the Texas Medical Center (TMC) and Uptown (including the Galleria). Of nearly 3 million non-farming jobs in the metropolitan area, 79 percent are concentrated in Harris County, according to the report. Approximately 2 million workers commute from somewhere within the region to Harris County every day; about half are high-wage workers (earning more than $40,000 annually), 30 percent are medium-wage workers ($15,000-$40,000 annually) and 19 percent are low-wage workers ($15,000 or less annually).In Harris County, about 47 percent of household income is spent on housing and transportation costs. When those burdens are considered, Houston is not very affordable compared to other cities, Wu said.“Few affordable units are found in major job centers, which makes it difficult for low-wage workers to rent close to where they work,” said Wu, who is also the director of research management at the Kinder Institute. “Compared to higher-wage workers, low-wage workers are more likely to live all over Harris County in neighborhoods that are poorly connected to job centers by transit. Affluent, suburban neighborhoods are well-served by park-and-ride and express buses to connect with the major job centers, but economically disadvantaged neighborhoods have limited or no public transit options as an alternative to driving to work.”The typical commute for residents in the Greater Houston area is 12.2 miles. On average, low-wage workers in Harris County travel 12.3 miles to downtown for work and 13.4 miles to the TMC or Uptown. The average commute for medium-wage earners in downtown, TMC or Uptown is 13 miles, 12.1 miles and 13 miles, respectively. For high-wage earners, the average commute distance is 14.4 miles to downtown, 12.5 miles to TMC and 12.4 miles to Uptown, the report read.The researchers hope the report will shed light on the need for the regional transportation network to be better connected to Houston’s job centers.“Policymakers should develop strategies to help low-income communities as well as urban and suburban communities of color to get investments needed to improve job accessibility and achieve equity in transportation,” the authors said. “On the other hand, housing options should be expanded within or near job centers, particularly around existing or planned public transit.”The report is available online at https://bit.ly/2EcmThe. In addition, the researchers created a web-based data tool to illustrate the dynamics between residences and employment centers. It is available online at http://www.datahouston.org/story/Commuting.html.-30-For more information, contact Amy McCaig, senior media relations specialist at Rice, at 713-348-6777 or amym@rice.edu.This news release can be found online at http://news.rice.edu/.Follow Rice News and Media Relations via Twitter @RiceUNews.Related Materials:Kinder Institute website: https://kinder.rice.edu/Photo link: https://cpb-us-e1.wpmucdn.com/news-network.rice.edu/dist/c/2/files/2018/10/75772657_l-21lz4fj.jpgPhoto credit: 123rf.com/Rice UniversityLocated on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation’s top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,970 undergraduates and 2,934 graduate students, Rice’s undergraduate student-to-faculty ratio is just under 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for lots of race/class interaction and No. 2 for quality of life by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger’s Personal Finance. To read “What they’re saying about Rice,” go to http://tinyurl.com/RiceUniversityoverview.center_img AddThislast_img read more


Penn State BOSS Program Honors A Decade of Promoting Diversity

first_img Last Updated Aug 24, 2017 by Jillian MarkowitzFacebookTwitterLinkedinemail RelatedSmeal Awards Merit-Based Financial Aid to 100 Percent of Incoming MBA ClassEvery student entering the MBA program at the Penn State Smeal College of Business received some level of financial aid based on merit this year, as both scholarships and graduate assistantships (GAs) increased. Support from the college, Penn State University and donor gifts made the record level of aid possible,…September 6, 2013In “Featured Region”Smeal MBA Students Attend Largest Career Fair in the USThirty four MBA students at Penn State University’s Smeal College of Business had the opportunity to attend the largest career fair in the country at the annual exposition and conference of the National Black MBA Association (NBMBAA) in Houston. The Smeal College of Business and Penn State University both contributed…November 11, 2013In “Featured Region”EMBA Helps Smeal Alum Achieve SuccessAfter being laid off from his job, Tony Pagano decided to invest in his education. Five years later, he had earned his EMBA from the Smeal College of Business at Penn State and founded his own company. Pagano is the founder and CEO of StrataScape Technologies, a next-generation IT service and support…April 15, 2015In “Featured Home” Penn State BOSS Program Honors A Decade of Promoting Diversity regions: Philadelphiacenter_img About the AuthorJillian MarkowitzView more posts by Jillian Markowitz Penn State’s Smeal College of Business recently celebrated the ten year anniversary of its BOSS program. BOSS (Business Opportunities Summer Session), organized by the Smeal College of Business Office of Diversity Enhancement Programs, lasts two weeks each summer, and is specifically designed for business-minded high schoolers from underrepresented populations to gain exposure to college life.Jamie Campbell, Assistant Dean for Diversity Enhancement Programs, said, “BOSS is designed to show students that no matter your color, creed, or socio-eceonomic background, there is a support system at Smeal that will enable a student to reach their very best.” Campbell went on to say that, “During these two weeks, students are given a crash course on what it means to be a Smeal student. BOSS engages the cohort in everything from accounting to the Smeal honor code.”According to Campbell, industries and schools are coming around to the fact that having including people from diverse backgrounds and perspectives is essential to success in business. Students in the program have the chance to take college prep courses, taught by Penn State faculty, that help them gain an understanding of fundamental business principles. Participants spend the two weeks living on Penn State’s University Park campus located in Happy Valley. Over the past decade, the BOSS program has inspired many successful students. Close to 200 students have attended the program, and over 60 percent of which have gone on to apply to Penn State. Of the BOSS graduates who have applied to Penn State, 91 percent have been accepted.Diag Davenport, one of the program’s earliest participants spoke highly of his time there, saying, “I left Penn State fully energized to study business and I was certain that Smeal was the right place for me to do so. I saw that BOSS was the bridge between my ambition to succeed and the opportunity to make it happen.”last_img read more